Precision Medicine

Flow Cytometry Technology & Applications

Discover the intricate science underpinning this innovative tool and explore its wide-ranging applications. Learn how this technology is revolutionising research, diagnostics, and therapeutics, and how our solutions can leverage its potential to drive your success.

Flow Cytometry

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Equipment and Technology for Flow Cytometry

At PeploBio, we utilize state-of-the-art flow cytometers and technology to ensure the quality and accuracy of our services. Our cutting-edge equipment, such as the BD FACSLyric™, allows us to provide unmatched results.
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BD FACSLyric™

The BD FACSLyric™ is a flow cytometry platform that combines exceptional performance with intuitive operation. This instrument represents the latest advancements in flow cytometry technology, providing robust analytical capabilities and high-quality data.
Multicolour Analysis: The BD FACSLyric™ supports multi-parameter analysis, allowing simultaneous detection of multiple markers on individual cells. This capability enables detailed phenotypic and functional profiling of cell populations, providing comprehensive insights into cellular interactions and immune responses.
Optimal Sensitivity and Resolution: The BD FACSLyric™ delivers exceptional sensitivity and resolution, enabling the detection and analysis of rare and low-abundance cell populations. This ensures precise and reliable characterisation of cellular subpopulations in complex samples.
High-Throughput Capabilities: With its high-throughput capabilities, the BD FACSLyric™ enables the analysis of large sample cohorts efficiently. This allows us to process a significant number of samples in a shorter time frame, providing faster results to support time-sensitive clinical trials.
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Applications of Flow Cytometry in Precision Medicine

Explore the multitude of applications where Flow Cytometry, utilizing a laser beam and fluorescent antibodies, finds its role in research, clinical diagnostics, and beyond. PeploBio's Flow Cytometry services can elevate your work across various fields:

Basophil Activation Test

The Basophil Activation Test (BAT), a cornerstone of allergy research and precision medicine, harnesses the capabilities of Flow Cytometry. Through the precision of Flow Cytometry and the harmonisation of international standards, BAT allows for the meticulous evaluation of basophil activation in response to allergens. This test plays a vital role in diagnosing allergies, aligning with technical harmonisation standards, and ensuring patients receive the most accurate and effective treatments.

Intracellular Cytokine Analysis

Intracellular Cytokine Analysis is at the forefront of immune cell research. By utilizing Flow Cytometry, researchers can delve into the intricate world of immune cells and their responses to various stimuli. This technique, in line with international harmonisation guidelines, enables the examination of intracellular cytokine production within individual immune cells. It aids in studying immune responses to pathogens, vaccines, and therapies, contributing to precision medicine.

Surface Profiling

Flow Cytometry plays a crucial role in surface profiling, allowing for the high-precision characterization of cell surface markers. This technique, guided by international harmonisation standards, utilizes fluorescent markers to identify and quantify specific molecules on cell surfaces. Researchers, complying with technical harmonisation, can use surface profiling to distinguish between cell types, monitor marker expression changes, and gain insights into disease progression and treatment effects.

Cell Enumeration

Flow Cytometry's precision extends to cell enumeration, a critical aspect of clinical diagnostics and immunology research. With international harmonisation in mind, this technique accurately quantifies cell populations in heterogeneous samples. Whether for clinical diagnostics, monitoring disease progression, or assessing treatment outcomes, precise cell enumeration ensures that immune cell analysis is aligned with technical harmonisation standards.

Cellular Phenotyping

Cellular Phenotyping, a pillar of immunology research, relies on Flow Cytometry for precision. This technique, in line with international harmonisation standards, enables the comprehensive characterization of immune cell populations. Researchers can assess cell types, surface markers, and functional properties with meticulous detail. Cellular phenotyping plays a pivotal role in understanding immune responses and advancing precision medicine.

Cellular Proliferation Assays

Cellular Proliferation Assays, employing Flow Cytometry, provide dynamic insights into cell growth and replication. Researchers, complying with international harmonisation, can track cell division and assess treatment effects. This precision enables the study of cell cycle dynamics, growth factors, and the influence of therapeutic interventions, contributing to precision medicine.

MDSC (Myeloid-Derived Suppressor Cell) Assays

MDSC Assays, powered by Flow Cytometry, delve into myeloid-derived suppressor cells—a key focus in cancer research. By quantifying MDSCs and assessing their immunosuppressive activity, researchers can explore immunosuppression dynamics within the tumor microenvironment. This precision aligns with international harmonisation principles and opens avenues for targeted immunomodulation in cancer therapy.

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